| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 24/09/25 18:45 | PAOK Salónica | Maccabi Tel Aviv | -:- |
| 24/09/25 18:45 | FC Midtjylland | SK Sturm Graz | -:- |
| 24/09/25 21:00 | Dinamo Zagreb | Fenerbahçe SK | -:- |
| 24/09/25 21:00 | Estrella Roja Belgrado | Celtic Glasgow | -:- |
| 24/09/25 21:00 | Sporting Braga | Feyenoord Rotterdam | -:- |
| 24/09/25 21:00 | Real Betis Balompié | Nottingham Forest | -:- |
| 24/09/25 21:00 | Malmö FF | PFC Ludogorets Razgrad | -:- |
| 24/09/25 21:00 | SC Freiburg | FC Basilea | -:- |
| 24/09/25 21:00 | OGC Niza | AS Roma | -:- |
| 25/09/25 18:45 | OSC Lille | Brann Bergen | -:- |
| 25/09/25 18:45 | Go Ahead Eagles Deventer | FCSB Bukarest | -:- |
| 25/09/25 21:00 | Glasgow Rangers | KRC Genk | -:- |
| 25/09/25 21:00 | Ferencvaros Budapest | Viktoria Pilsen | -:- |
| 25/09/25 21:00 | Young Boys Berna | Panathinaikos Athenas | -:- |
| 25/09/25 21:00 | Aston Villa | FC Bologna | -:- |
| 25/09/25 21:00 | FC Red Bull Salzburgo | FC Porto | -:- |
| 25/09/25 21:00 | FC Utrecht | Olympique Lyon | -:- |
| 25/09/25 21:00 | VfB Stuttgart | R. C. Celta de Vigo | -:- |